About
A reference, not a storefront.
Peptide Guide is a research-oriented reference for therapeutic peptides: mechanism, dosing, and evidence quality, presented without the sales pitch.
This site is for educational and research purposes only. Nothing here is medical advice. Always consult a qualified healthcare provider before using any peptide or supplement.
What this is
Peptide Guide organizes the full landscape of therapeutic peptides into an intuitive, browsable knowledge base. It’s a wiki, not a shop. Every entry links what a peptide does, how it works, the quality of the evidence, and practical protocol details drawn from published research, FDA records, and clinical trial data.
Editorial standards
Three commitments shape every entry on this site:
- EvidenceTiers and ratings are decided from primary sources (peer-reviewed trials, FDA records, clinical-trial registries) before any commercial relationship and never adjusted to favor a partner.
- IndependenceThe supplier directory and per-compound sourcing notes list providers based on credentials and regulatory record, not who pays. Affiliate placements, when present, sit in clearly labeled modules separate from editorial content. See the full affiliate disclosure.
- CurrencyRegulatory posture and the supplier landscape change quickly. Compound entries carry a last updated date and the supplier directory runs an automated audit against OpenFDA every 24 hours.
Methodology: how we rate evidence
Every peptide has one of four evidence tiers:
- EstablishedFDA-approved for at least one indication with extensive human trial data.
- ClinicalActive or completed human clinical trials (Phase I–III).
- PreclinicalStrong animal model data, limited or no controlled human trials.
- ExperimentalEarly research, anecdotal, or insufficient data to characterize.
Non-peptide compounds
Some compounds on this site (Cardarine, DMAA, Tadalafil, methylene blue, and others) are not strictly peptides but are commonly discussed alongside peptides in the optimization community. They are clearly labeled and included for reference.
Limits of this resource
Peptide science evolves quickly. Regulatory posture (FDA compounding rules, WADA lists, scheduling) changes frequently. We update entries periodically, but anyone relying on this information should verify against primary sources.