Gut Health & GI

Intestinotrophic peptide that stimulates intestinal growth and nutrient absorption; approved analog teduglutide is used in short bowel syndrome.

Synthetic octapeptide zonulin antagonist that blocks tight-junction disassembly. Phase 3 CedLara trial for celiac was terminated for futility in June 2022.

Synthetic 28-aa vasoactive intestinal peptide. FDA denied EUA twice for COVID-19; orphan designation for ARDS and pulmonary hypertension.

Endogenous 37-aa cationic antimicrobial peptide with immunomodulatory, wound healing, and angiogenic effects.

Khavinson liver/bronchi tripeptide proposed to modulate hepatocyte proliferation and immune-cell activity. Studied for chronic hepatitis.