◆ Latest: Retatrutide Phase 3 trial reports 24% weight reduction at 48 wks◆ Established: 10 peptides now FDA approved for metabolic indications◆ Preclinical: BPC-157 meta-analysis (17 rodent studies) published◆ Evidence: new mitochondrial peptide review covers MOTS-c, SS-31, Humanin◆ Safety: hCG supply disruption update, Q2 2026◆ Editorial: The Mitochondrial Decade, new long-read◆ Latest: Retatrutide Phase 3 trial reports 24% weight reduction at 48 wks◆ Established: 10 peptides now FDA approved for metabolic indications◆ Preclinical: BPC-157 meta-analysis (17 rodent studies) published◆ Evidence: new mitochondrial peptide review covers MOTS-c, SS-31, Humanin◆ Safety: hCG supply disruption update, Q2 2026◆ Editorial: The Mitochondrial Decade, new long-read

Definition

Polyphenol

A broad family of plant-derived compounds containing multiple phenol rings, including flavonoids, lignans, and tannins. Urolithin A is a gut-microbiome-derived polyphenol metabolite that induces mitophagy.

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