§ 01 Overview
Overview
Oral capsule form of GHK-Cu marketed for systemic skin and connective tissue support.
Oral bioavailability questionable; no trial data.
§ 02 Mechanism
Mechanism of action
Oral GHK-Cu bioavailability is uncertain due to GI peptidase activity. Any systemic effects would reflect the broader gene-expression modulating and collagen-stimulating effects of the GHK-Cu complex.
- 01Convenience vs. injectable or topical
- 02Systemic copper peptide exposure (claimed)
§ 03 Dosing
Dosing protocol
Standard Protocol
- Dose Range
- Manufacturer-specified
- Route
- Oral
- Frequency
- Daily
§ 04 Evidence
Evidence & research
Oral bioavailability questionable; no trial data.
FDA Status
Cosmetic ingredient; oral capsule form not FDA-approved.
§ 07 Sourcing
Sourcing & supply
Regulatory status
Restricted from compounding
Placed on the FDA's 503A Category 2 list and cannot be lawfully compounded in the US. No brand pharmacy alternative exists. US buyers encounter only research-use-only (RUO) channels, which the FDA's Intended Use Doctrine treats as unapproved drug sales.
No suppliers in our directory currently stock this compound. For investigational or research-only compounds, legitimate channels may not exist outside clinical trials.
Browse full supplier directory§ 09 Safety
Safety & side effects
Side effects
- 01Copper accumulation if taken long-term at high doses
Contraindications
None specified.