§ 01 Overview
Overview
Tetrapeptide developed by Russian researcher Khavinson; investigated for telomerase activation and pineal function support.
Russian studies report telomerase and lifespan effects. Limited independent replication in Western labs.
§ 02 Mechanism
Mechanism of action
Epitalon is hypothesized to induce telomerase expression and modulate pineal peptide signaling. Reported effects on melatonin rhythm and antioxidant enzymes in animal studies.
- 01Telomere length support (preclinical)
- 02Circadian rhythm and melatonin support anecdotally
- 03Reported lifespan extension in rodent studies
§ 03 Dosing
Dosing protocol
Standard Protocol
- Vial
- 10 mg
- BAC Water
- 2 ml BAC water
- Dose Range
- 5 – 10 mg per cycle, split daily
- Starting Dose
- 5 mg/day for 10–20 days
- Route
- SubQ
- Timing
- PM
- Frequency
- Daily
- Cycle
- 10–20 day courses, 1–2x per year
§ 04 Evidence
Evidence & research
Russian studies report telomerase and lifespan effects. Limited independent replication in Western labs.
FDA Status
Not FDA-approved.
§ 05 Stacks
Common stacks
§ 06 News
In the news
8 articles from the last 12 months · updates hourly
FDA panel gives nod to six controversial peptides - The Washington Post
FDA panel gives nod to six controversial peptides The Washington Post
FDA Advisory Panel Votes Against Emideltide While Backing Epitalon And Semax For Compounding - londoninsider.co.uk
FDA Advisory Panel Votes Against Emideltide While Backing Epitalon And Semax For Compounding londoninsider.co.uk
FDA advisers narrowly vote to add 6 peptides to a drug compounding list. What's next? - ABC News - Breaking News, Latest News and Videos
FDA advisers narrowly vote to add 6 peptides to a drug compounding list. What's next? ABC News - Breaking News, Latest News and Videos
FDA advisers recommend relaxing US rules on compounding peptides - Reuters
FDA advisers recommend relaxing US rules on compounding peptides Reuters
FDA advisory committee backs two more peptides, rejects one for compounding list - RAPS
FDA advisory committee backs two more peptides, rejects one for compounding list RAPS
FDA Panel Finds a Peptide It Doesn't Like - MedPage Today
FDA Panel Finds a Peptide It Doesn't Like MedPage Today
FDA advisory panel narrowly rejects compounding of one peptide, backs two others - STAT
FDA advisory panel narrowly rejects compounding of one peptide, backs two others STAT
FDA advisers say six popular peptides can be compounded. Here are the issues they considered. - MarketWatch
FDA advisers say six popular peptides can be compounded. Here are the issues they considered. MarketWatch
§ 07 Sourcing
Sourcing & supply
Regulatory status
Restricted from compounding
Placed on the FDA's 503A Category 2 list and cannot be lawfully compounded in the US. No brand pharmacy alternative exists. US buyers encounter only research-use-only (RUO) channels, which the FDA's Intended Use Doctrine treats as unapproved drug sales.
Telehealth (Rx) · 1
Defy Medical
Rx requiredBroadest peptide formulary in legitimate US telehealth. 13-year history, concierge cash-pay, no known lawsuits.
International · 5
Cosmic Nootropic
The most credible Russian / Khavinson source for US buyers. Sources authentic bioregulators through 'Peptides Company' (ex-NPCRIZ).
Rupharma
12+ year Russian pharmacy reseller. Reviews.io 4.84/5 (81+). Has a genuine US warehouse for common peptides.
Trident Peptides
1,299+ Trustpilot reviews (5-star). Strongest review base in UK research peptides. No visible ISO/GMP; COAs not posted.
Direct Peptides
Multi-region geo-routed mirrors. Multiple credible scam complaints. Documented customs seizures. Avoid absent stronger evidence.
Pharma Lab Global
Budget pricing but significant QC concerns. Claims HPLC+MS 'on request' not displayed.
Research-use-only · 6
Swiss Chems
Established SARMs/peptide vendor. FDA warning letter Dec 2024 for GLP-1s. Weaker peptide QC than SARMs QC.
Limitless Life Nootropics
'Only BBB-accredited peptide company' (since 2020). Claims three-lab third-party testing. Broad catalog.
Core Peptides
Broad catalog, widest payment range. Mid-credibility: Knoji 2.5/5 and one scam-impersonation report.
Ascension Peptides
Among newer RUO vendors with cleaner credibility signals. SafeCert Labs (CLIA-certified) testing, 4.8 Trustpilot. US-only.
Modern Aminos
Multi-vial batch third-party testing. 5-star Trustpilot (1,400+ reviews). US- and EU-facing.
Peptide Warehouse
US-made, independent third-party testing including endotoxin and heavy-metal panels. Distinct from similar-sounding copycat domains.
Listings are informational, not endorsement. Verify credentials and flags against FDA and PCAB databases before purchasing. Full directory & how to verify →
§ 09 Safety
Safety & side effects
Side effects
- 01Rare; data limited
Contraindications
None specified.
§ 10 Questions
Epitalon FAQ
- What is Epitalon?
- Tetrapeptide developed by Russian researcher Khavinson; investigated for telomerase activation and pineal function support. Epitalon is hypothesized to induce telomerase expression and modulate pineal peptide signaling. Reported effects on melatonin rhythm and antioxidant enzymes in animal studies.
- What is Epitalon used for?
- Reported uses include telomere length support (preclinical), circadian rhythm and melatonin support anecdotally, and reported lifespan extension in rodent studies. Evidence strength is rated Preclinical — see the evidence section for detail.
- How is Epitalon dosed?
- Commonly referenced dosing is 5 – 10 mg per cycle, split daily, administered SubQ. This is educational reference only; consult a licensed clinician before use.
- How do you reconstitute Epitalon?
- For Epitalon, vials commonly come in 10 mg and a common reconstitution is 2 ml BAC water. Use the reconstitution calculator to convert any vial size and water volume into exact insulin-syringe units.
- What are the side effects of Epitalon?
- Commonly reported side effects include rare; data limited. This list is not exhaustive.
- Is Epitalon legal?
- Placed on the FDA's 503A Category 2 list and cannot be lawfully compounded in the US. No brand pharmacy alternative exists. US buyers encounter only research-use-only (RUO) channels, which the FDA's Intended Use Doctrine treats as unapproved drug sales. FDA status: Not FDA-approved..