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EstablishedGrowth HormoneSubQDaily

Tesamorelin

Egrifta

FDA-approved GHRH analog that specifically reduces visceral adipose tissue (VAT), originally developed for HIV-associated lipodystrophy.

Read dosing protocol

§ 01   Overview

Overview

FDA-approved GHRH analog that specifically reduces visceral adipose tissue (VAT), originally developed for HIV-associated lipodystrophy.

FDA-approved 2010 for HIV-associated lipodystrophy. Extensive Phase III data; off-label use for VAT reduction.

§ 02   Mechanism

Mechanism of action

Tesamorelin is a stabilized GHRH(1-44) analog. It stimulates endogenous GH release and preferentially reduces visceral fat, with favorable effects on IGF-1 and hepatic fat.

  • 01Targeted visceral fat reduction (15–20% VAT decrease)
  • 02Improved liver fat markers
  • 03Lean mass preservation

§ 03   Dosing

Dosing protocol

Standard Protocol

Vial
1 mg or 2 mg
BAC Water
1 ml BAC water per vial
Dose Range
1 – 2 mg daily
Starting Dose
1 mg daily
Route
SubQ
Timing
Before bed
Frequency
Daily
Cycle
12–26 weeks; reassess IGF-1

§ 04   Evidence

Evidence & research

Established

FDA-approved 2010 for HIV-associated lipodystrophy. Extensive Phase III data; off-label use for VAT reduction.

FDA Status

FDA-approved (HIV lipodystrophy).

§ 05   Stacks

Common stacks

Ipamorelin

GH pulse amplification

§ 06   News

In the news

8 articles from the last 12 months · updates hourly

§ 07   Sourcing

Sourcing & supply

Regulatory status

FDA-approved

This compound has an FDA approval for at least one indication. Brand pharmacy channels exist. Compounding may or may not be available depending on shortage status.

503B pharmacies · 5

503B pharmacy

Empower Pharmacy

Rx required

One of the largest US compounders by volume; dual 503A + 503B. Repeat FDA enforcement history and ongoing Lilly litigation.

FDA 503B Registered6 flags on record
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503B pharmacy

Olympia Pharmaceuticals

Rx required

35+ year family-owned dual 503A/503B licensed in 48–49 states. Among the cleanest mid-sized 503Bs operating today.

FDA 503B Registered3 flags on record
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503B pharmacy

Belmar Pharma Solutions

Rx required

Webster Equity portfolio. Triple-credentialed (PCAB + NABP + LegitScript), licensed in all 50 states. Among the most credentialed operators.

FDA 503B Registered +31 flag on record
503B pharmacy

Fagron Sterile Services

Rx required

Established 503B outsourcing facility in FDA's registered list.

FDA 503B Registered
503B pharmacy

Wedgewood Connect

Rx required

FDA-registered 503B outsourcing facility.

FDA 503B Registered

Telehealth (Rx) · 1

Telehealth

Defy Medical

Rx required

Broadest peptide formulary in legitimate US telehealth. 13-year history, concierge cash-pay, no known lawsuits.

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Research-use-only · 3

Research-use-only

Swiss Chems

Established SARMs/peptide vendor. FDA warning letter Dec 2024 for GLP-1s. Weaker peptide QC than SARMs QC.

Third-Party Testing1 flag on record
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Research-use-only

Limitless Life Nootropics

'Only BBB-accredited peptide company' (since 2020). Claims three-lab third-party testing. Broad catalog.

BBB Accredited +1
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Research-use-only

Core Peptides

Broad catalog, widest payment range. Mid-credibility: Knoji 2.5/5 and one scam-impersonation report.

Third-Party Testing1 flag on record
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Listings are informational, not endorsement. Verify credentials and flags against FDA and PCAB databases before purchasing. Full directory & how to verify →

§ 09   Safety

Safety & side effects

Side effects

  • 01Injection site erythema
  • 02Arthralgia
  • 03Elevated IGF-1

Contraindications

  • 01Active malignancy
  • 02Pituitary disorders
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AOD-9604

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Oral capsule form of AOD-9604 with limited bioavailability compared to injectable form.

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CJC-1295 + Ipamorelin

Classic GHRH + GHRP combination that amplifies endogenous GH pulses more than either alone.

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This site is for educational and research purposes only. It does not constitute medical advice. Always consult a qualified healthcare provider before using any peptide or supplement.