§ 01 Overview
Overview
Stack combining the FDA-approved GHRH analog Tesamorelin with Ipamorelin for amplified GH pulses and targeted visceral fat reduction.
Stack used in compounding. Tesamorelin alone has FDA data; the combination does not.
§ 02 Mechanism
Mechanism of action
Tesamorelin provides sustained GHRH receptor activation while Ipamorelin adds a ghrelin receptor pulse, amplifying endogenous GH release.
- 01Visceral fat reduction (Tesamorelin) + GH pulse amplification (Ipamorelin)
- 02Favorable body composition in users
§ 03 Dosing
Dosing protocol
Standard Protocol
- Vial
- Combo vial
- BAC Water
- 2 ml BAC water
- Dose Range
- 10 – 20 units (0.1 – 0.2 ml)
- Route
- SubQ
- Timing
- Before bed
- Frequency
- Daily
- Cycle
- 8–12 weeks
§ 04 Evidence
Evidence & research
Stack used in compounding. Tesamorelin alone has FDA data; the combination does not.
FDA Status
Components: Tesamorelin FDA-approved; Ipamorelin not.
§ 05 Stacks
Common stacks
§ 06 News
In the news
1 article from the last 12 months · updates hourly
Andrew Huberman on Peptide Stacking, GLP-1s, and the Gila Monster That Changed Weight Loss - Goop
Andrew Huberman on Peptide Stacking, GLP-1s, and the Gila Monster That Changed Weight Loss Goop
§ 07 Sourcing
Sourcing & supply
Regulatory status
Restricted from compounding
Placed on the FDA's 503A Category 2 list and cannot be lawfully compounded in the US. No brand pharmacy alternative exists. US buyers encounter only research-use-only (RUO) channels, which the FDA's Intended Use Doctrine treats as unapproved drug sales.
No suppliers in our directory currently stock this compound. For investigational or research-only compounds, legitimate channels may not exist outside clinical trials.
Browse full supplier directory§ 09 Safety
Safety & side effects
Side effects
- 01Injection site reactions
- 02Elevated IGF-1
Contraindications
None specified.
§ 10 Questions
Tesamorelin + Ipamorelin FAQ
- What is Tesamorelin + Ipamorelin?
- Stack combining the FDA-approved GHRH analog Tesamorelin with Ipamorelin for amplified GH pulses and targeted visceral fat reduction. Tesamorelin provides sustained GHRH receptor activation while Ipamorelin adds a ghrelin receptor pulse, amplifying endogenous GH release.
- What is Tesamorelin + Ipamorelin used for?
- Reported uses include visceral fat reduction (tesamorelin) + gh pulse amplification (ipamorelin) and favorable body composition in users. Evidence strength is rated Preclinical — see the evidence section for detail.
- How is Tesamorelin + Ipamorelin dosed?
- Commonly referenced dosing is 10 – 20 units (0.1 – 0.2 ml), typically daily, administered SubQ. This is educational reference only; consult a licensed clinician before use.
- How do you reconstitute Tesamorelin + Ipamorelin?
- For Tesamorelin + Ipamorelin, vials commonly come in Combo vial and a common reconstitution is 2 ml BAC water. Use the reconstitution calculator to convert any vial size and water volume into exact insulin-syringe units.
- What are the side effects of Tesamorelin + Ipamorelin?
- Commonly reported side effects include injection site reactions and elevated igf-1. This list is not exhaustive.
- Is Tesamorelin + Ipamorelin legal?
- Placed on the FDA's 503A Category 2 list and cannot be lawfully compounded in the US. No brand pharmacy alternative exists. US buyers encounter only research-use-only (RUO) channels, which the FDA's Intended Use Doctrine treats as unapproved drug sales. FDA status: Components: Tesamorelin FDA-approved; Ipamorelin not..