§ 01 Overview
Overview
Synthetic pentapeptide (Arg-Lys-Asp-Val-Tyr) corresponding to residues 32–36 of thymopoietin. Approved in Italy and China for immune modulation in chronic infection, rheumatoid arthritis, and hepatitis B; not FDA-approved.
Multiple European / Asian controlled trials. Italian RA and HBV studies. Not FDA-approved; limited Western post-2000 literature.
§ 02 Mechanism
Mechanism of action
Thymopentin represents the minimum active region of thymopoietin. It binds surface receptors on T-cell precursors to promote maturation and regulate helper/suppressor balance, with anti-inflammatory and antiviral adjunct effects.
- 01Immune modulation in chronic HBV, HCV, and RA
- 02Studied as adjuvant in HIV and post-op infection
- 03Approved in several non-US jurisdictions
§ 03 Dosing
Dosing protocol
Standard Protocol
- Vial
- 50 mg
- BAC Water
- 2 ml BAC water or per product
- Dose Range
- 50 mg per dose
- Route
- SubQ
- Frequency
- 3× weekly
- Cycle
- 4–12 weeks typical
§ 04 Evidence
Evidence & research
Multiple European / Asian controlled trials. Italian RA and HBV studies. Not FDA-approved; limited Western post-2000 literature.
FDA Status
Not FDA-approved. Approved in Italy and China.
§ 06 News
In the news
1 article from the last 12 months · updates hourly
Thymopentin enhances adenoviral oncolytic therapy by regulating macrophages and CD8 - Nature
Thymopentin enhances adenoviral oncolytic therapy by regulating macrophages and CD8 Nature
§ 07 Sourcing
Sourcing & supply
Regulatory status
Authentic supply from international sources
Authentic product originates from specific international manufacturers, most commonly Russian pharmaceutical facilities for Khavinson bioregulators. RUO vendors selling the same name are typically Chinese-synthesized research vials, not the original product.
No suppliers in our directory currently stock this compound. For investigational or research-only compounds, legitimate channels may not exist outside clinical trials.
Browse full supplier directory§ 09 Safety
Safety & side effects
Side effects
- 01Injection site reactions
- 02Transient fatigue
Contraindications
None specified.
§ 10 Questions
Thymopentin FAQ
- What is Thymopentin?
- Synthetic pentapeptide (Arg-Lys-Asp-Val-Tyr) corresponding to residues 32–36 of thymopoietin. Approved in Italy and China for immune modulation in chronic infection, rheumatoid arthritis, and hepatitis B; not FDA-approved. Thymopentin represents the minimum active region of thymopoietin. It binds surface receptors on T-cell precursors to promote maturation and regulate helper/suppressor balance, with anti-inflammatory and antiviral adjunct effects.
- What is Thymopentin used for?
- Reported uses include immune modulation in chronic hbv, hcv, and ra, studied as adjuvant in hiv and post-op infection, and approved in several non-us jurisdictions. Evidence strength is rated Clinical — see the evidence section for detail.
- How is Thymopentin dosed?
- Commonly referenced dosing is 50 mg per dose, typically 3× weekly, administered SubQ. This is educational reference only; consult a licensed clinician before use.
- How do you reconstitute Thymopentin?
- For Thymopentin, vials commonly come in 50 mg and a common reconstitution is 2 ml BAC water or per product. Use the reconstitution calculator to convert any vial size and water volume into exact insulin-syringe units.
- What are the side effects of Thymopentin?
- Commonly reported side effects include injection site reactions and transient fatigue. This list is not exhaustive.
- Is Thymopentin legal?
- Authentic product originates from specific international manufacturers, most commonly Russian pharmaceutical facilities for Khavinson bioregulators. RUO vendors selling the same name are typically Chinese-synthesized research vials, not the original product. FDA status: Not FDA-approved. Approved in Italy and China..
§ 11 References
Selected references
- 01
Goldstein — thymopentin biology
Ann NY Acad Sci 1988
- 02
Bolla — HBV adjunct
J Hepatol 1990