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Peptide.Guide
EstablishedSexual HealthSubQ2–3x weekly

HCG

Human Chorionic Gonadotropin

Pituitary-like gonadotropin that mimics LH, used in fertility, hypogonadism, and post-TRT recovery protocols.

Read dosing protocol

§ 01   Overview

Overview

Pituitary-like gonadotropin that mimics LH, used in fertility, hypogonadism, and post-TRT recovery protocols.

FDA-approved for fertility and hypogonadotropic hypogonadism. Well-characterized.

§ 02   Mechanism

Mechanism of action

HCG binds the LH receptor on Leydig cells (in men) to stimulate endogenous testosterone and progesterone synthesis, and on granulosa cells (in women) to support ovulation.

  • 01Stimulates endogenous testosterone in men on TRT
  • 02Preserves testicular function and fertility on TRT
  • 03Induces ovulation in fertility protocols

§ 03   Dosing

Dosing protocol

Standard Protocol

Dose Range
250 – 750 IU per dose (TRT adjunct)
Starting Dose
250 IU
Route
SubQ
Timing
Any time
Frequency
2–3x weekly
Cycle
Alongside TRT or for fertility cycles

§ 04   Evidence

Evidence & research

Established

FDA-approved for fertility and hypogonadotropic hypogonadism. Well-characterized.

FDA Status

FDA-approved (fertility, hypogonadism).

§ 06   News

In the news

8 articles from the last 12 months · updates hourly

§ 07   Sourcing

Sourcing & supply

Regulatory status

FDA-approved

This compound has an FDA approval for at least one indication. Brand pharmacy channels exist. Compounding may or may not be available depending on shortage status.

503B pharmacies · 2

503B pharmacy

Empower Pharmacy

Rx required

One of the largest US compounders by volume; dual 503A + 503B. Repeat FDA enforcement history and ongoing Lilly litigation.

FDA 503B Registered6 flags on record
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503B pharmacy

Fagron Sterile Services

Rx required

Established 503B outsourcing facility in FDA's registered list.

FDA 503B Registered

Telehealth (Rx) · 1

Telehealth

Fountain TRT / Fountain Vitality

Rx required

Urologist-led TRT + GLP-1 platform. 4-star Trustpilot. Distinct from Fountain Life.

Visit

Listings are informational, not endorsement. Verify credentials and flags against FDA and PCAB databases before purchasing. Full directory & how to verify →

§ 09   Safety

Safety & side effects

Side effects

  • 01Elevated estrogen (men)
  • 02Gynecomastia risk
  • 03Injection site reactions

Contraindications

None specified.

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This site is for educational and research purposes only. It does not constitute medical advice. Always consult a qualified healthcare provider before using any peptide or supplement.