Skip to content
Peptide.Guide
EstablishedSexual HealthSubQ2–3x weekly

HCG

Human Chorionic Gonadotropin

Pituitary-like gonadotropin that mimics LH, used in fertility, hypogonadism, and post-TRT recovery protocols.

§ 01   Overview

Overview

Pituitary-like gonadotropin that mimics LH, used in fertility, hypogonadism, and post-TRT recovery protocols.

FDA-approved for fertility and hypogonadotropic hypogonadism. Well-characterized.

§ 02   Mechanism

Mechanism of action

HCG binds the LH receptor on Leydig cells (in men) to stimulate endogenous testosterone and progesterone synthesis, and on granulosa cells (in women) to support ovulation.

  • 01Stimulates endogenous testosterone in men on TRT
  • 02Preserves testicular function and fertility on TRT
  • 03Induces ovulation in fertility protocols

§ 03   Dosing

Dosing protocol

Standard Protocol

Dose Range
250 – 750 IU per dose (TRT adjunct)
Starting Dose
250 IU
Route
SubQ
Timing
Any time
Frequency
2–3x weekly
Cycle
Alongside TRT or for fertility cycles

§ 04   Evidence

Evidence & research

Established

FDA-approved for fertility and hypogonadotropic hypogonadism. Well-characterized.

FDA Status

FDA-approved (fertility, hypogonadism).

§ 06   News

In the news

8 articles from the last 12 months · updates hourly

§ 07   Sourcing

Sourcing & supply

Regulatory status

FDA-approved

This compound has an FDA approval for at least one indication. Brand pharmacy channels exist. Compounding may or may not be available depending on shortage status.

503B pharmacies · 2

503B pharmacy

Empower Pharmacy

Rx required

One of the largest US compounders by volume; dual 503A + 503B. Repeat FDA enforcement history and ongoing Lilly litigation.

FDA 503B Registered6 flags on record
Visit
503B pharmacy

Fagron Sterile Services

Rx required

Established 503B outsourcing facility in FDA's registered list.

FDA 503B Registered

Telehealth (Rx) · 1

Telehealth

Fountain TRT / Fountain Vitality

Rx required

Urologist-led TRT + GLP-1 platform. 4-star Trustpilot. Distinct from Fountain Life.

Visit

Listings are informational, not endorsement. Verify credentials and flags against FDA and PCAB databases before purchasing. Full directory & how to verify →

§ 09   Safety

Safety & side effects

Side effects

  • 01Elevated estrogen (men)
  • 02Gynecomastia risk
  • 03Injection site reactions

Contraindications

None specified.

This site is for educational and research purposes only. It does not constitute medical advice. Always consult a qualified healthcare provider before using any peptide or supplement.