§ 01 Overview
Overview
Porcine brain-derived multi-peptide preparation with neurotrophic-factor-like activity. Used in ~50 countries for stroke, TBI, and vascular dementia.
Cochrane review 2013 is cautious. CARS trial showed early functional benefit.
§ 02 Mechanism
Mechanism of action
Cerebrolysin is a standardized preparation of low-molecular-weight neuropeptides and amino acids derived from porcine brain. It mimics BDNF/GDNF/CNTF activity, shows anti-apoptotic effects, and modulates amyloid processing in AD models.
- 01Functional improvement in moderate-severe ischemic stroke (CARS)
- 02Widely used internationally for TBI and vascular dementia
§ 03 Dosing
Dosing protocol
Standard Protocol
- Dose Range
- 10 – 30 ml per course (trial protocols)
- Route
- IM
- Frequency
- Daily for 10–21 days
- Cycle
- 2–4 courses per year
§ 04 Evidence
Evidence & research
Cochrane review 2013 is cautious. CARS trial showed early functional benefit.
FDA Status
Not FDA-approved. Approved in many EU and Asian markets.
§ 06 News
In the news
1 article from the last 12 months · updates hourly
Cerebrolysin IV Therapy Now Available at NexGen Health in Silicon Valley - PR Newswire
Cerebrolysin IV Therapy Now Available at NexGen Health in Silicon Valley PR Newswire
§ 07 Sourcing
Sourcing & supply
Regulatory status
Authentic supply from international sources
Authentic product originates from specific international manufacturers, most commonly Russian pharmaceutical facilities for Khavinson bioregulators. RUO vendors selling the same name are typically Chinese-synthesized research vials, not the original product.
International · 2
Cosmic Nootropic
The most credible Russian / Khavinson source for US buyers. Sources authentic bioregulators through 'Peptides Company' (ex-NPCRIZ).
Rupharma
12+ year Russian pharmacy reseller. Reviews.io 4.84/5 (81+). Has a genuine US warehouse for common peptides.
Research-use-only · 1
Limitless Life Nootropics
'Only BBB-accredited peptide company' (since 2020). Claims three-lab third-party testing. Broad catalog.
Listings are informational, not endorsement. Verify credentials and flags against FDA and PCAB databases before purchasing. Full directory & how to verify →
§ 09 Safety
Safety & side effects
Side effects
- 01Injection site reactions
- 02Transient dizziness or agitation
- 03Rare hypersensitivity
Contraindications
None specified.
§ 10 Questions
Cerebrolysin FAQ
- What is Cerebrolysin?
- Porcine brain-derived multi-peptide preparation with neurotrophic-factor-like activity. Used in ~50 countries for stroke, TBI, and vascular dementia. Cerebrolysin is a standardized preparation of low-molecular-weight neuropeptides and amino acids derived from porcine brain. It mimics BDNF/GDNF/CNTF activity, shows anti-apoptotic effects, and modulates amyloid processing in AD models.
- What is Cerebrolysin used for?
- Reported uses include functional improvement in moderate-severe ischemic stroke (cars) and widely used internationally for tbi and vascular dementia. Evidence strength is rated Clinical — see the evidence section for detail.
- How is Cerebrolysin dosed?
- Commonly referenced dosing is 10 – 30 ml per course (trial protocols), typically daily for 10–21 days, administered IM. This is educational reference only; consult a licensed clinician before use.
- What are the side effects of Cerebrolysin?
- Commonly reported side effects include injection site reactions, transient dizziness or agitation, and rare hypersensitivity. This list is not exhaustive.
- Is Cerebrolysin legal?
- Authentic product originates from specific international manufacturers, most commonly Russian pharmaceutical facilities for Khavinson bioregulators. RUO vendors selling the same name are typically Chinese-synthesized research vials, not the original product. FDA status: Not FDA-approved. Approved in many EU and Asian markets..
§ 11 References
Selected references
- 01
Cochrane stroke review
PMID: 23440886
- 02
CARS trial
PMID: 29098642 (NCT01044693)