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Peptide.Guide

FDA Category 2 · restricted from compounding

This compound is on the FDA’s interim Section 503A Category 2 bulks list and cannot be legally compounded by US pharmacies. An HHS announcement in February 2026 signaled intent to restore several peptides to Category 1, but no Federal Register action has been published. Check the FDA PCAC schedule for updates.

Read the full regulatory context
PreclinicalCognitiveIntranasalDaily

Selank

Synthetic tuftsin analog with anxiolytic and immunomodulatory effects, developed as a non-benzodiazepine alternative.

§ 01   Overview

Overview

Synthetic tuftsin analog with anxiolytic and immunomodulatory effects, developed as a non-benzodiazepine alternative.

Russian clinical use for generalized anxiety. Limited Western data.

§ 02   Mechanism

Mechanism of action

Selank modulates GABAergic tone, expression of BDNF, and enkephalin metabolism. It produces anxiolytic effects without sedation or dependence in animal and early human studies.

  • 01Anxiety reduction without sedation
  • 02Improved stress resilience
  • 03Modest nootropic effects

§ 03   Dosing

Dosing protocol

Standard Protocol

Vial
5 mg
BAC Water
1 ml BAC water
Dose Range
250 – 900 mcg per dose
Starting Dose
300 mcg intranasal
Route
Intranasal
Timing
AM or during stress
Frequency
Daily
Cycle
2–4 weeks

§ 04   Evidence

Evidence & research

Preclinical

Russian clinical use for generalized anxiety. Limited Western data.

FDA Status

Not FDA-approved.

§ 05   Stacks

Common stacks

§ 06   News

In the news

2 articles from the last 12 months · updates hourly

§ 07   Sourcing

Sourcing & supply

Regulatory status

Restricted from compounding

Placed on the FDA's 503A Category 2 list and cannot be lawfully compounded in the US. No brand pharmacy alternative exists. US buyers encounter only research-use-only (RUO) channels, which the FDA's Intended Use Doctrine treats as unapproved drug sales.

International · 3

International

Cosmic Nootropic

The most credible Russian / Khavinson source for US buyers. Sources authentic bioregulators through 'Peptides Company' (ex-NPCRIZ).

Visit
International

Rupharma

12+ year Russian pharmacy reseller. Reviews.io 4.84/5 (81+). Has a genuine US warehouse for common peptides.

Visit
International

Trident Peptides

1,299+ Trustpilot reviews (5-star). Strongest review base in UK research peptides. No visible ISO/GMP; COAs not posted.

1 flag on record
Visit

Research-use-only · 4

Research-use-only

Swiss Chems

Established SARMs/peptide vendor. FDA warning letter Dec 2024 for GLP-1s. Weaker peptide QC than SARMs QC.

Third-Party Testing1 flag on record
Visit
Research-use-only

Limitless Life Nootropics

'Only BBB-accredited peptide company' (since 2020). Claims three-lab third-party testing. Broad catalog.

BBB Accredited +1
Visit
Research-use-only

Core Peptides

Broad catalog, widest payment range. Mid-credibility: Knoji 2.5/5 and one scam-impersonation report.

Third-Party Testing1 flag on record
Visit
Research-use-only

Modern Aminos

Multi-vial batch third-party testing. 5-star Trustpilot (1,400+ reviews). US- and EU-facing.

Third-Party Testing
Visit

Listings are informational, not endorsement. Verify credentials and flags against FDA and PCAB databases before purchasing. Full directory & how to verify →

§ 09   Safety

Safety & side effects

Side effects

  • 01Mild nasal irritation

Contraindications

None specified.

This site is for educational and research purposes only. It does not constitute medical advice. Always consult a qualified healthcare provider before using any peptide or supplement.