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ExperimentalCognitiveOralAs usedFDA-banned; serious cardiovascular events reportedPartial data

DMAA

1,3-Dimethylamylamine

Potent sympathomimetic stimulant once sold in pre-workout supplements; banned by the FDA in dietary supplements due to safety concerns.

◆ Editorial note

Sympathomimetic stimulant, not a peptide. Banned by FDA in dietary supplements.

§ 01   Overview

Overview

Potent sympathomimetic stimulant once sold in pre-workout supplements; banned by the FDA in dietary supplements due to safety concerns.

Linked to serious adverse events including strokes and deaths in healthy users.

§ 02   Mechanism

Mechanism of action

DMAA is a synthetic vasoconstrictor and releaser of norepinephrine, producing stimulant, appetite-suppressing, and pressor effects.

  • 01Strong stimulant and focus effects (subjective)
  • 02Appetite suppression

§ 03   Dosing

Dosing protocol

Standard Protocol

Dose Range
25 – 75 mg (historic pre-workout doses)
Route
Oral
Frequency
As used

§ 04   Evidence

Evidence & research

Experimental

Linked to serious adverse events including strokes and deaths in healthy users.

FDA Status

FDA declared DMAA illegal in dietary supplements (2013).

§ 06   News

In the news

8 articles from the last 12 months · updates hourly

§ 07   Sourcing

Sourcing & supply

Regulatory status

Research-only, no commercial channel

No commercial channel exists. Available only as a research reagent from RUO suppliers. Use in humans is not established.

No suppliers in our directory currently stock this compound. For investigational or research-only compounds, legitimate channels may not exist outside clinical trials.

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§ 09   Safety

Safety & side effects

Side effects

  • 01Severe hypertension
  • 02Strokes and deaths reported
  • 03Cardiac arrhythmias

Contraindications

  • 01Cardiovascular disease
  • 02Hypertension
  • 03Any stimulant sensitivity

§ 10   Questions

DMAA FAQ

What is DMAA?
Potent sympathomimetic stimulant once sold in pre-workout supplements; banned by the FDA in dietary supplements due to safety concerns. DMAA is a synthetic vasoconstrictor and releaser of norepinephrine, producing stimulant, appetite-suppressing, and pressor effects.
What is DMAA used for?
Reported uses include strong stimulant and focus effects (subjective) and appetite suppression. Evidence strength is rated Experimental — see the evidence section for detail.
How is DMAA dosed?
Commonly referenced dosing is 25 – 75 mg (historic pre-workout doses), typically as used, administered Oral. This is educational reference only; consult a licensed clinician before use.
What are the side effects of DMAA?
Commonly reported side effects include severe hypertension, strokes and deaths reported, and cardiac arrhythmias. This list is not exhaustive.
Is DMAA legal?
No commercial channel exists. Available only as a research reagent from RUO suppliers. Use in humans is not established. FDA status: FDA declared DMAA illegal in dietary supplements (2013)..

This site is for educational and research purposes only. It does not constitute medical advice. Always consult a qualified healthcare provider before using any peptide or supplement.