§ 01 Overview
Overview
Potent sympathomimetic stimulant once sold in pre-workout supplements; banned by the FDA in dietary supplements due to safety concerns.
Linked to serious adverse events including strokes and deaths in healthy users.
§ 02 Mechanism
Mechanism of action
DMAA is a synthetic vasoconstrictor and releaser of norepinephrine, producing stimulant, appetite-suppressing, and pressor effects.
- 01Strong stimulant and focus effects (subjective)
- 02Appetite suppression
§ 03 Dosing
Dosing protocol
Standard Protocol
- Dose Range
- 25 – 75 mg (historic pre-workout doses)
- Route
- Oral
- Frequency
- As used
§ 04 Evidence
Evidence & research
Linked to serious adverse events including strokes and deaths in healthy users.
FDA Status
FDA declared DMAA illegal in dietary supplements (2013).
§ 06 News
In the news
8 articles from the last 12 months · updates hourly
Supplement Powder Recall: FDA Warns of Potential ‘Cardiovascular Problems’ - Yahoo News Singapore
Supplement Powder Recall: FDA Warns of Potential ‘Cardiovascular Problems’ Yahoo News Singapore
15 years ago BSN introduced its creatine and DMAA-free concentrated pre-workout Hyper FX - Stack3d
15 years ago BSN introduced its creatine and DMAA-free concentrated pre-workout Hyper FX Stack3d
Drugs Made In America Acquisition (DMAA) Stock Price, News & Analysis - Stock Titan
Drugs Made In America Acquisition (DMAA) Stock Price, News & Analysis Stock Titan
Behind the Scoop: What the Rapture Pre-Workout Recall Reveals About Supplement Safety - Men's Fitness
Behind the Scoop: What the Rapture Pre-Workout Recall Reveals About Supplement Safety Men's Fitness
Pre-workout powder recalled over illegal stimulant linked to heart attacks - The Independent
Pre-workout powder recalled over illegal stimulant linked to heart attacks The Independent
Pre-workout powder recalled over illegal stimulant - Upper Michigan's Source
Pre-workout powder recalled over illegal stimulant Upper Michigan's Source
Pre-workout powder recalled over illegal stimulant - ABC7 WWSB
Pre-workout powder recalled over illegal stimulant ABC7 WWSB
Rapture Preworkout Users Should Check Lot 260327-4 After FDA Testing Finds Unlisted Stimulant DMAA in Three Flavors - Medical Daily
Rapture Preworkout Users Should Check Lot 260327-4 After FDA Testing Finds Unlisted Stimulant DMAA in Three Flavors Medical Daily
§ 07 Sourcing
Sourcing & supply
Regulatory status
Research-only, no commercial channel
No commercial channel exists. Available only as a research reagent from RUO suppliers. Use in humans is not established.
No suppliers in our directory currently stock this compound. For investigational or research-only compounds, legitimate channels may not exist outside clinical trials.
Browse full supplier directory§ 09 Safety
Safety & side effects
Side effects
- 01Severe hypertension
- 02Strokes and deaths reported
- 03Cardiac arrhythmias
Contraindications
- 01Cardiovascular disease
- 02Hypertension
- 03Any stimulant sensitivity
§ 10 Questions
DMAA FAQ
- What is DMAA?
- Potent sympathomimetic stimulant once sold in pre-workout supplements; banned by the FDA in dietary supplements due to safety concerns. DMAA is a synthetic vasoconstrictor and releaser of norepinephrine, producing stimulant, appetite-suppressing, and pressor effects.
- What is DMAA used for?
- Reported uses include strong stimulant and focus effects (subjective) and appetite suppression. Evidence strength is rated Experimental — see the evidence section for detail.
- How is DMAA dosed?
- Commonly referenced dosing is 25 – 75 mg (historic pre-workout doses), typically as used, administered Oral. This is educational reference only; consult a licensed clinician before use.
- What are the side effects of DMAA?
- Commonly reported side effects include severe hypertension, strokes and deaths reported, and cardiac arrhythmias. This list is not exhaustive.
- Is DMAA legal?
- No commercial channel exists. Available only as a research reagent from RUO suppliers. Use in humans is not established. FDA status: FDA declared DMAA illegal in dietary supplements (2013)..