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Peptide.Guide
ExperimentalCognitiveOralPartial data

Fladrafinil

CRL-40,941

Fluorinated analog of adrafinil/modafinil with similar wakefulness-promoting effects. Research chemical status.

◆ Editorial note

Bisfluoro analog of adrafinil. Not a peptide.

§ 01   Overview

Overview

Fluorinated analog of adrafinil/modafinil with similar wakefulness-promoting effects. Research chemical status.

Essentially no controlled human data. Research chemical.

§ 02   Mechanism

Mechanism of action

Fladrafinil is a prodrug believed to metabolize similarly to adrafinil, producing modafinil-like wakefulness via weak dopamine reuptake inhibition and histaminergic effects.

  • 01Wakefulness and focus
  • 02Potential reduced hepatic load vs. adrafinil (claimed)

§ 03   Dosing

Dosing protocol

Standard Protocol

Dose Range
Unknown standardized dosing
Route
Oral

§ 04   Evidence

Evidence & research

Experimental

Essentially no controlled human data. Research chemical.

FDA Status

Not FDA-approved. Research chemical.

§ 07   Sourcing

Sourcing & supply

Regulatory status

Research-only, no commercial channel

No commercial channel exists. Available only as a research reagent from RUO suppliers. Use in humans is not established.

No suppliers in our directory currently stock this compound. For investigational or research-only compounds, legitimate channels may not exist outside clinical trials.

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§ 09   Safety

Safety & side effects

Side effects

  • 01Unknown; likely similar to modafinil class

Contraindications

None specified.

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