§ 01 Overview
Overview
Dipeptide-ester nootropic (Russian Rx) that metabolizes to cycloprolylglycine and elevates BDNF/NGF.
Russian clinical literature (Ostrovskaya 2002, 2007).
§ 02 Mechanism
Mechanism of action
Noopept is hydrolyzed to cycloprolylglycine, an endogenous dipeptide that stabilizes BDNF/NGF and exerts anxiolytic and anti-amnestic effects. It is used in Russia for cognitive decline and post-concussive states.
- 01Anti-amnestic effects (preclinical and Russian clinical)
- 02Anxiolytic at low doses
- 03Oral bioavailability
§ 03 Dosing
Dosing protocol
Standard Protocol
- Dose Range
- 10 – 30 mg daily
- Route
- Oral
- Timing
- AM or split AM/PM
- Frequency
- Daily
- Cycle
- 4–8 weeks
§ 04 Evidence
Evidence & research
Russian clinical literature (Ostrovskaya 2002, 2007).
FDA Status
Not FDA-approved. Registered in Russia for cognitive decline.
§ 07 Sourcing
Sourcing & supply
Regulatory status
Authentic supply from international sources
Authentic product originates from specific international manufacturers, most commonly Russian pharmaceutical facilities for Khavinson bioregulators. RUO vendors selling the same name are typically Chinese-synthesized research vials, not the original product.
International · 2
Cosmic Nootropic
The most credible Russian / Khavinson source for US buyers. Sources authentic bioregulators through 'Peptides Company' (ex-NPCRIZ).
Rupharma
12+ year Russian pharmacy reseller. Reviews.io 4.84/5 (81+). Has a genuine US warehouse for common peptides.
Listings are informational, not endorsement. Verify credentials and flags against FDA and PCAB databases before purchasing. Full directory & how to verify →
§ 09 Safety
Safety & side effects
Side effects
- 01Irritability in some users
- 02Headache
- 03Sleep disruption at higher doses
Contraindications
None specified.
§ 10 Questions
Noopept FAQ
- What is Noopept?
- Dipeptide-ester nootropic (Russian Rx) that metabolizes to cycloprolylglycine and elevates BDNF/NGF. Noopept is hydrolyzed to cycloprolylglycine, an endogenous dipeptide that stabilizes BDNF/NGF and exerts anxiolytic and anti-amnestic effects. It is used in Russia for cognitive decline and post-concussive states.
- What is Noopept used for?
- Reported uses include anti-amnestic effects (preclinical and russian clinical), anxiolytic at low doses, and oral bioavailability. Evidence strength is rated Clinical — see the evidence section for detail.
- How is Noopept dosed?
- Commonly referenced dosing is 10 – 30 mg daily, administered Oral. This is educational reference only; consult a licensed clinician before use.
- What are the side effects of Noopept?
- Commonly reported side effects include irritability in some users, headache, and sleep disruption at higher doses. This list is not exhaustive.
- Is Noopept legal?
- Authentic product originates from specific international manufacturers, most commonly Russian pharmaceutical facilities for Khavinson bioregulators. RUO vendors selling the same name are typically Chinese-synthesized research vials, not the original product. FDA status: Not FDA-approved. Registered in Russia for cognitive decline..
§ 11 References
Selected references
- 01
Ostrovskaya Exp Clin Pharmacol 2002
PMID: 12596357
- 02
Ostrovskaya 2007
PMID: 17538146